During mechanical ventilation changes in heart and lung physiology take place the cardiopulmonary interactions in mechanical ventilation are different with respect to normal breathing conditions in critical care medicine it is crucial to understand the basic concepts of cardiopulmonary interactions to optimise treatment. After this brief review of essential features we may discuss some aspects of the interactions between heart and lung function influence of intrathoracic pressure the importance of transmural pressure it is established that blood pressure volume and flow rates in the lesser circula tion change during each respiratory cycle. American journal of respiratory and critical care medicine home all ajrccm issues vol 195 no 9 may 01 2017 a randomized trial of low tidal volume ventilation in cardiac arrest survivors for example would ideally be designed with specific mechanisms of benefit in mind trzeciak s emergency medicine shock research network . Lung protective ventilation strategies and adjunctive treatments for the emergency medicine patient with acute respiratory failure brian j wright md mphab introduction invasive mechanical ventilation mv is an essential component of critical care and lung protective ventilation strategies and adjunctive treatments for the emergency . Acute respiratory distress syndrome ards is a condition of acute inflammatory lung injury that causes non cardiogenic pulmonary edema by increasing alveolar capillary permeability the thickened diffusion barrier leads to decreased lung compliance inefficient gas exchange increased physiological dead space and subsequently hypoxemia 12
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